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Although the treated mice did not develop more skin tumors than similar mice that had not been fed the antioxidants, they developed twice as many tumors in their lymph nodes, a hallmark of the spread of cancera process called metastasis

Other methods of measuring catalase activity have been developed, including those involving iodometry [19] chemiluminescence [14], polarimetry [15], and monitoring the production of oxygen via an oxygen electrode [20] or a low-flow gas meter [21]

Smith PG, Venis MA, Hall MA (1985) Oxidation of ethylene by cotyledon extracts from Vicia faba L.: cofactor requirements and kinetics

Deletion polymorphisms of genes encoding GSTM1 and GSTT1 are widely found in humans