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ZG and HZ drafted the manuscript, figures and tables

The age-related decline in IFN- production [245], which increases the risk of viral infections, highlights the significance of findings by Cakman et al., who demonstrated that in vitro supplementation of blood from elderly individuals with 15 M zinc significantly enhanced IFN- production [167]

Natural food sources of MSM include coffee, tea, and some dairy products, though concentrations are generally low

Testing how the application of exogenous GABA in tea plants affects the respiration pathway of amino acid biosynthesis through reverse genetic pathway under low temperature, is further needed