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In organotypic hippocampal slice cultures, Dihexa and Nle-AngIV similarly augmented spinogenesis, with control slices showing 7 spines per 50-m dendrite length, compared to 11 for both Dihexa and Nle-AngIV treated slices [2]

What they did: A two-phase study, first in a dish with human endothelial cells (HUVECs), then in a live rat with an ischemic limb (= they closed off the artery so that no blood reached the leg)