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Up to 50% of patients will develop a neuropathy and it can occur relatively early on in the first few courses, typically plateauing by cycle five

The skin and mucous membranes are often bypassed, so that pallor, abnormal pigmentation, icterus, spider nevi, petechiae, purpura, angiomas, ulcerations, palmar erythema, coarseness of hair, puffiness of the face, thinning of the lateral aspects of the eyebrows, and nail defects are missed in the rush to examine the heart and the lungs (Maakaron & Besa, 2021)

Understanding the trial results at each dose level helps you set realistic expectations and choose the right maintenance dose for your goals

These cases gain strength when doctors identify a timeline where symptoms begin soon after a vaccination such as influenza, tetanus or human papillomavirus