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Additionally, hyponatremia-induced reduction in extracellular osmotic pressure and resultant cerebral edema are deemed significant contributors to hepatic encephalopathy development, with a reported 8% increase in hepatic encephalopathy risk for every 1 mmol/L reduction in serum sodium (Iwasa and Takei, 2015

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To be consistent with SAMHSA's reforms to telehealth flexibilities for initiation of treatment with methadone at 8.12(f)(2)(B)(v), past conforming regulations under the Medicare OTP benefit to allow telecommunication flexibilities for initiation of treatment with buprenorphine, and to contribute towards efforts to reduce barriers in accessing care for Medicare beneficiaries seeking treatment with methadone, we proposed to make similar telecommunication flexibilities under the Medicare OTP benefit in the ( CY 2025 PFS proposed rule