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This is known in functional medicine as the "NAC Paradox." While NAC provides the raw cysteine needed for the body to build its own glutathione, clinical observations indicate that NAC can act as a direct histamine liberator in sensitive individuals

10.1016/j.cardfail.2007.06.721 63 MehtaS

We recently demonstrated that in young adults, 200 mg of paraxanthine, compared to a placebo, can acutely affect short-term memory, reasoning, and response times to cognitive challenges (Yoo et al

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