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Common side effects associated with B12 supplementation include: Local injection site reactions (for intramuscular preparations): Pain, redness, or swelling at the injection site Mild bruising or tenderness Itching localised to the injection area These reactions are usually self-limiting and resolve within 2448 hours

It has been widely studied in preclinical models for its potential to support tissue regeneration , angiogenesis , and inflammation modulation

To this end, we isolated bacterial DNA from paired stool samples of both OSKM-expressing mice and wild-type (WT) littermate control mice before and after 7 days of doxycycline treatment, and performed shotgun metagenome sequencing 20 (Extended Data Fig