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Description

Metastatic colorectal carcinoma-associated fibroblasts have immunosuppressive properties related to increased IGFBP2 expression

It helps optimize the activity of immune cells, such as lymphocytes and macrophages, allowing them to combat infections and foreign invaders effectively

Li WZ, Huo QJ, Wang XY, Xu F

After filtration and concentration, the obtained crude product was purified by chromatography on silica gel with ethyl acetate/petroleum ether (1/3, v/v) to give an orange solid product 16 (365 mg, 56%)