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However, with direct injection, if you do not need the additional B12, it may result in high levels in your blood that can cause side effects including gastrointestinal issues, headache and dizziness, tiredness and weakness, or skin irritation until the excess is flushed out via your kidneys and urine

Note that our body is not very efficient at absorbing vitamin B12 from supplements, so it's better to stay on the safe side by aiming to consume well over the minimum recommended amount, rather than taking a little less or sticking to the RDI

Nat Struct Biol 1:143144 Chillemi A, Quarona V, Antonioli L, Ferrari D, Horenstein AL, Malavasi F (2017) Roles and modalities of ectonucleotidases in remodeling the multiple myeloma niche

TGF-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis