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The data are presented as heatmaps of z-score normalized abundances for the significantly different metabolites across all groups (Fig

An increase in dihydroxyacetone phosphate (DHAP) (ratio: 1.5) was also observed

demonstrated that oxidative modification by ROS formed 8-oxoguanine in miRNAs seed regions, which led to adenine mispairing mutation with mRNA, and promoted cardiac hypertrophy