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For the skeletal muscle system , it was found that spermidine intake does not affect skeletal muscle regeneration after chemical injury or hypertrophy 123,124 , but it can protect muscle or delay muscle loss, acting through autophagy mechanisms and improving mitochondrial integrity, and attenuating structural deterioration of muscle fibre 125,126

Some studies on the effects of APP treatment on blood have primarily focused on coagulation 16

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