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The premise underlying the leaky gut hypothesis is that physiologic stressors such as anxiety, intensive exercise, or dietary components such as emulsifiers increase intestinal mucosal paracellular permeability, enhancing entry of pathogenic bacteria and bacterial toxins into the systemic circulation, provoking systemic inflammation and triggering numerous diseases

Oxidative stress continues to be one of the strongest influencers in the development of conditions such as Parkinsons disease

Patient Suitability: Adults vs Neonates One of the most critical distinctions relates to patient safety

Hardison et al., 2018a) have attempted to understand this discrepancy through transient haem-iron restriction of NTHi