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Over time, this oxidative insult accumulates and diminishes both follicle number and quality, presenting as premature menopause or a suboptimal response to ovarian stimulation

Frequent antibiotic use wipes out healthy gut bacteria along with harmful ones, disrupting the microbiome balance

Biomarkers of effects caused by iodine are discussed in Section 3.9.2

A2-APM treatment efficacy is dependent on CD8 + T cells Since our results above demonstrated that T cells play an important role in A2-APM anti-GBM efficacy, next we investigated which subtype of T cells (CD4 or CD8) plays a dominant role in A2-APM antitumor therapy