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doi: 10.7150/ijms.86622

Such symptoms have resulted from the over-stimulation of the thyroid due to the induction of hyperthyroidism through exogenous thyroid hormones and in turn cause excessive secretion of thyroid hormones, which disturb the feedback loop of the hypothalamic-pituitary-thyroid axis (Bao et al

References 25 and 26 show that, contrary to the results of cell-based experiments relating Ser307 phosphorylation of IRS1 to impaired insulin signalling, Ser307 in mice is a positive regulatory site that maintains proximal insulin signalling

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